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Mepacrine

CAS No. 83-89-6

Mepacrine( —— )

Catalog No. M34002 CAS No. 83-89-6

Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial. It is used in cell biological experiments as an inhibitor of phospholipase A2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 178 Get Quote
5MG 256 Get Quote
10MG 375 Get Quote
25MG 545 Get Quote
50MG 762 Get Quote
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Biological Information

  • Product Name
    Mepacrine
  • Note
    Research use only, not for human use.
  • Brief Description
    Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial. It is used in cell biological experiments as an inhibitor of phospholipase A2.
  • Description
    Quinacrine (Acriquine) is an antimalarial and anti-cancer agent. Quinacrine also inhibits human aldehyde oxidase (IC50: 3.3 μM). Quinacrine has affinity for nucleic acids, and stains DNA and RNA in fixed cells (Ex/Em: 436/525 nm).
  • In Vitro
    Cell Viability Assay Cell Line:SGC-7901 cell Concentration:0, 5, 10, 15, 20 μM Incubation Time:24 h Result:Inhibited cell growth with an IC50 value of 16.18 μM.
  • In Vivo
    Animal Model:Acute kidney injury rat model Dosage:3-30 mg/kg Administration:i.p.Result:Attenuated glycerol induced structural and functional changes in kidney.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    83-89-6
  • Formula Weight
    399.96
  • Molecular Formula
    C23H30ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(CCCN(CC)CC)C)C=1C2=C(N=C3C1C=CC(Cl)=C3)C=CC(OC)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vogtherr M, et al. Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein. J Med Chem. 2003 Aug 14;46(17):3563-4. ?
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