CYM50260
CAS No. 1355026-60-6
CYM50260( —— )
Catalog No. M23514 CAS No. 1355026-60-6
CYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 119 | In Stock |
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| 5MG | 107 | In Stock |
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| 10MG | 180 | In Stock |
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| 25MG | 376 | In Stock |
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| 50MG | 551 | In Stock |
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| 100MG | 784 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCYM50260
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NoteResearch use only, not for human use.
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Brief DescriptionCYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM).
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DescriptionCYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM). CYM50260 shows no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.
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In VitroCYM50260 (Compound 22aa) is a synthetic S1P4-R agonist. CYM50260 is found 3.5-fold more potent than the hit compound (HTS-hit).CYM50260 suppresses the collagen-stimulated platelet aggregation, PDGF-AB secretion and sCD40L release. CYM50260 reduces the release of phosphorylated-HSP27 by collagen as well as the phosphorylation of HSP27.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorS1P4-R
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Research Area——
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Indication——
Chemical Information
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CAS Number1355026-60-6
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Formula Weight350.6
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Molecular FormulaC14H11Cl3FNO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (356.53 mM)
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SMILESFCC1=CC=C(OCCOC2=CC=C(Cl)C=C2Cl)C(Cl)=N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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(E)-Tonghaosu
The herbs of Glebionis coronaria.
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Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.
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Haspin-IN-3
Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
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