Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - DNA Alkylator - Melphalan

Melphalan

CAS No. 148-82-3

Melphalan( L-PAM )

Catalog No. M12056 CAS No. 148-82-3

A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Melphalan
  • Note
    Research use only, not for human use.
  • Brief Description
    A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.
  • Description
    A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.Chemotherapeutic Agents Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    L-PAM
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    DNA Alkylator
  • Research Area
    Cancer
  • Indication
    Chemotherapeutic

Chemical Information

  • CAS Number
    148-82-3
  • Formula Weight
    305.2002
  • Molecular Formula
    C13H18Cl2N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: < 9.2 mg/mL
  • SMILES
    N[C@@H](CC1=CC=C(N(CCCl)CCCl)C=C1)C(O)=O
  • Chemical Name
    L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dudek-Peri? AM, et al. Cancer Res. 2015 Apr 15;75(8):1603-14. 2. Keane MM, et al. Cancer Res. 1999 Feb 1;59(3):734-41.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Carboplatin

    A chemotherapy agent that interferes with DNA replication and kills cancer cells; induces growth arrest and/or apoptosis in most cancer cell types; an alkylating agent for treatment of a number of cancers.

  • Satraplatin

    Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis.

  • Mitomycin C

    Mitomycin C (Ametycine) is a chemotherapeutic antibiotic that acts as a double-stranded DNA alkylating agent.

Sign In Join Free