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Melphalan

CAS No. 148-82-3

Melphalan ( L-PAM )

Catalog No. M12056 CAS No. 148-82-3

A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Melphalan
Note

Research use only, not for human use.
Brief Description

A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.
Description

A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells. Chemotherapeutic Agents Approved
Synonyms

L-PAM
Pathway

Cell Cycle/DNA Damage
Target

DNA Alkylator
Recptor

DNA Alkylator
Research Area

Cancer
Indication

Chemotherapeutic

Chemical Information

CAS Number

148-82-3
Formula Weight

305.20
Molecular Formula

C13H18Cl2N2O2
Purity

>98% (HPLC)
Solubility

DMSO: < 9.2 mg/mL
SMILES

N[C@@H](CC1=CC=C(N(CCCl)CCCl)C=C1)C(O)=O
Chemical Name

L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dudek-Peri AM, et al. Cancer Res. 2015 Apr 15;75(8):1603-14.
2. Keane MM, et al. Cancer Res. 1999 Feb 1;59(3):734-41.

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