Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - DNA Alkylator - Satraplatin

Satraplatin

CAS No. 129580-63-8

Satraplatin ( BMS-182751;BMY-45594;JM-216 )

Catalog No. M11196 CAS No. 129580-63-8

Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 293 In Stock
10MG 426 In Stock
25MG 699 In Stock
50MG 981 In Stock
100MG 1314 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Satraplatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis.
  • Description
    Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis; shows similar cytotoxicity and pattern of cytotoxicity to cisplatin against human ovarian carcinoma cell lines (IC50=1.7 uM); shows antitumor selectivity far superior to cisplatin, carboplatin, or tetraplatin in vivo; orally active. Chemotherapeutic Agents, Phase 2 Clinical
  • Synonyms
    BMS-182751;BMY-45594;JM-216
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    DNA Alkylator
  • Research Area
    Cancer
  • Indication
    Chemotherapeutic

Chemical Information

  • CAS Number
    129580-63-8
  • Formula Weight
    500.28
  • Molecular Formula
    C10H22Cl2N2O4Pt+2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 33 mg/mL
  • SMILES
    CC(O[Pt]([NH2]C1CCCCC1)(Cl)(Cl)([NH3])OC(C)=O)=O
  • Chemical Name
    Platinum, bis(acetato-κO)amminedichloro(cyclohexanamine)-, (OC-6-43)- (9CI)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kelland LR, et al. Cancer Res. 1993 Jun 1;53(11):2581-6.
2. Mellish KJ, et al. Br J Cancer. 1993 Aug;68(2):240-50.
3. Ricart AD, et al. Clin Cancer Res. 2009 Jun 1;15(11):3866-71.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Oxaliplatin

    A platinum-based antineoplastic agent that works by blocking the duplication of DNA; forms both inter- and intra-strand cross links in DNA, prevents DNA replication and transcription, causing cell death.

  • Quinacrine dihydroch...

    An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years.

  • Alchemix

    A dual action as an alkylating agent and topoisomerase inhibitor with potent activity against anthracycline- and cisplatin-resistant tumor cancer.

Sign In Join Free