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Maritoclax
CAS No. 1227962-62-0
Maritoclax ( Marinopyrrole A )
Catalog No. M23400 CAS No. 1227962-62-0
Maritoclax (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
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| 5MG | 80 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 264 | In Stock |
|
| 50MG | 492 | In Stock |
|
| 100MG | 687 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMaritoclax
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NoteResearch use only, not for human use.
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Brief DescriptionMaritoclax (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor.
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DescriptionMaritoclax (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor, shows >8 fold selectivity than BCL-xl (IC50 >?80 μM),with an IC50 value of 10.1 μM.
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SynonymsMarinopyrrole A
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PathwayAngiogenesis
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TargetBcl-2
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RecptorMcl-1
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Research Area——
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Indication——
Chemical Information
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CAS Number1227962-62-0
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Formula Weight510.2
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Molecular FormulaC22H12Cl4N2O4
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Purity>98% (HPLC)
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SolubilityDMSO:43 mg/mL (84.29 mM)
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SMILESC1=CC=C(C(=C1)C(=O)C2=CC(=C(N2C3=C(NC(=C3Cl)Cl)C(=O)C4=CC=CC=C4O)Cl)Cl)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Doi K, et al. Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation. J Biol Chem. 2012 Mar 23;287(13):10224-35.
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