Madrasin

CAS No. 374913-63-0

Madrasin ( DDD00107587; Madrasin. RNA splicing inhibitor )

Catalog No. M17498 CAS No. 374913-63-0

Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 54 In Stock
10MG 82 In Stock
25MG 156 In Stock
50MG 259 In Stock
100MG 466 In Stock
500MG 1008 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Madrasin
  • Note
    Research use only, not for human use.
  • Brief Description
    Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
  • Description
    Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin stalls spliceosome assembly at the A complex.
  • Synonyms
    DDD00107587; Madrasin. RNA splicing inhibitor
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Transferase
  • Recptor
    Others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    374913-63-0
  • Formula Weight
    311.34
  • Molecular Formula
    C16H17N5O2
  • Purity
    98%
  • Solubility
    H2O : < 0.1 mg/mL
  • SMILES
    O=c1[nH]c(Nc2nc(C)c3ccc(OC)cc3n2)nc(C)c1C
  • Chemical Name
    2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Andrea Pawellek et al. J Biol Chem, 2014 Dec 12, 289(50): 34683-34698.
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