MS436

CAS No. 1395084-25-9

MS436 ( MS436; MS-436; MS 436 )

Catalog No. M11651 CAS No. 1395084-25-9

MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 33 In Stock
5MG 53 In Stock
10MG 95 In Stock
25MG 183 In Stock
50MG 327 In Stock
100MG 478 In Stock
500MG 1035 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MS436
  • Note
    Research use only, not for human use.
  • Brief Description
    MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.
  • Description
    MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.
  • Synonyms
    MS436; MS-436; MS 436
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    BRD4 (1); BRD4 (2)
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1395084-25-9
  • Formula Weight
    383.42
  • Molecular Formula
    C18H17N5O3S
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 1 mg/mL warmed (2.6 mM); DMSO: 55 mg/mL (143.44 mM)
  • SMILES
    O=S(C1=CC=C(/N=N/C2=CC(C)=C(O)C=C2N)C=C1)(NC3=NC=CC=C3)=O
  • Chemical Name
    (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang G, et al. J Med Chem. 2013 Nov 27;56(22):9251-64.
molnova catalog
related products
  • Oxyphencyclimine Hyd...

    Oxyphencyclimine Hydrochloride is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.

  • MS645

    MS645 is an inhibitor of bromodomain-containing protein 4 (BRD4) with a Ki of 18.4 nM for BRD4-BD1/BD2.

  • NEO2734

    NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).