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MOSLOFLAVONE

CAS No. 740-33-0

MOSLOFLAVONE( —— )

Catalog No. M20486 CAS No. 740-33-0

MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and ?7.8 μM respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MOSLOFLAVONE
  • Note
    Research use only, not for human use.
  • Brief Description
    MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and ?7.8 μM respectively.
  • Description
    MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and ?7.8 μM respectively.
  • In Vitro
    Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    TNF-α|IL-1β
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    740-33-0
  • Formula Weight
    298.29
  • Molecular Formula
    C17H14O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (167.62 mM)
  • SMILES
    COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Singh B Sidiq T Joshi P et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.[J]. Natural Product Research 2013 27(23):2227-2230.
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