Danshensu

Research use only, not for human use.

Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.

Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.

Cell Migration Assay Cell Line:FaDu and Ca9-22 cells Concentration:25, 50, and 100 μM Incubation Time:24 h Result:At higher concentrations (50 and 100 μM) caused significant reduction in migration and invasion of both FaDu and Ca9-22 cells.Western Blot Analysis Cell Line:FaDu and Ca9-22 cells Concentration:25, 50, and 100 μM Incubation Time:24 h Result:Phosphorylation of ERK reduced dose-dependently after 24 h in FaDu cell. Caused significant reduction in p38 phosphorylation.

Animal Model:Adult BALB/c mice (male, 6-8 weeks, 20±2?g)Dosage:25, 50, 100?mg/kg Administration:Oral administration (daily for 7 continuous days) or i.v. (once) Result:Could prevent SARS-CoV-2 S protein-induced acute lung inflammation. Ameliorated inflammatory cytokines in serum and lung tissue.

Dan shen suan A | Salvianic acid A

Apoptosis

TNF

Others

Cardiovascular Disease

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76822-21-4

198.17

C9H10O5

>98% (HPLC)

H2O : 6.2 mg/mL 31.29 mM

c1cc(c(cc1C[C@H](C(=O)O)O)O)O

——

(-20℃)

With Ice Pack

≥ 2 years