MLT943

CAS No. 1832576-04-1

MLT943( —— )

Catalog No. M23833 CAS No. 1832576-04-1

MLT-943 is a potent, selective and orally active?MALT1 protease?inhibitor.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 237 In Stock
10MG 356 In Stock
25MG 597 In Stock
50MG 851 In Stock
100MG 1152 In Stock
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Biological Information

  • Product Name
    MLT943
  • Note
    Research use only, not for human use.
  • Brief Description
    MLT-943 is a potent, selective and orally active?MALT1 protease?inhibitor.?
  • Description
    MLT-943 is a potent, selective and orally active?MALT1 protease?inhibitor.?
  • In Vitro
    ——
  • In Vivo
    Animal Model:Na?ve rats Dosage:5 mg/kg Administration:Oral gavage; 5 mg/kg, 10 consecutive days or 0.1 mg/kg MLT-943 Result:Induced a severe immune-mediated pathology after a prolonged treatment
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    MALT1
  • Recptor
    MALT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1832576-04-1
  • Formula Weight
    414.77
  • Molecular Formula
    C16H14ClF3N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:247 mg/mL?(595.51 mM;?Need ultrasonic)
  • SMILES
    O=C(NC1=CC(C(F)(F)F)=NC=C1)NC2=C([C@@H](OC)C)N3C(N=C2)=CC(Cl)=N3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kea Martin, et al. Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology. Front Immunol
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