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Home - Products - GPCR/G Protein - Antibacterial - ML406

ML406

CAS No. 774589-47-8

ML406 ( ML406; ML-406; ML 406 )

Catalog No. M15926 CAS No. 774589-47-8

ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ML406
  • Note
    Research use only, not for human use.
  • Brief Description
    ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity.
  • Description
    ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity, dispalys >100-fold selectivity over bioD; exhibits WT M. tb (H37Rv) growth inhibition without biotin with an IC50 of 3.2 uM.
  • Synonyms
    ML406; ML-406; ML 406
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    774589-47-8
  • Formula Weight
    352.39
  • Molecular Formula
    C20H20N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C1=CC=C(N2CCN(C(C3=CC=C(OCO4)C4=C3)=O)CC2)C=C1)=O
  • Chemical Name
    1-(4-(4-(Benzo[d][1,3]dioxole-5-carbonyl)piperazin-1-yl)phenyl)ethanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Casalena D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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