ML318

CAS No. 1610516-67-0

ML318 ( —— )

Catalog No. M22095 CAS No. 1610516-67-0

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 67 Get Quote
5MG 110 Get Quote
10MG 178 Get Quote
25MG 403 Get Quote
50MG 592 Get Quote
100MG 844 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ML318
  • Note
    Research use only, not for human use.
  • Brief Description
    ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
  • Description
    ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PvdQ acylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1610516-67-0
  • Formula Weight
    280.22
  • Molecular Formula
    C14H8F4N2?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jacqueline M Wurst, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014 Jul 18;9(7):1536-44.
molnova catalog
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