ML-109 ( —— )

Catalog No. M21973 CAS No. 1186649-91-1

ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)ML-109 is a full agonist at TSHR with an EC50 of 40 nM,has no activity at FSHR or LHCGR.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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2MG	39	In Stock
5MG	65	In Stock
10MG	110	In Stock
25MG	222	In Stock
50MG	356	In Stock
100MG	533	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ML-109
Note

Research use only, not for human use.
Brief Description

ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)ML-109 is a full agonist at TSHR with an EC50 of 40 nM,has no activity at FSHR or LHCGR.
Description

ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)ML-109 is a full agonist at TSHR with an EC50 of 40 nM ,has no activity at FSHR or LHCGR.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

thyrotropin receptor (TSHR)
Research Area

——
Indication

——

Chemical Information

CAS Number

1186649-91-1
Formula Weight

523.58
Molecular Formula

C31H29N3O5
Purity

>98% (HPLC)
Solubility

DMSO:83.33 mg/mL (159.15 mM; Need ultrasonic)
SMILES

COc1ccc(cc1COc1ccc(NC(C)=O)cc1)C1Nc2cccc(O)c2C(=O)N1Cc1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12471-6.

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