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ML-109

CAS No. 1186649-91-1

ML-109 ( —— )

Catalog No. M21973 CAS No. 1186649-91-1

ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)ML-109 is a full agonist at TSHR with an EC50 of 40 nM,has no activity at FSHR or LHCGR.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 39 In Stock
5MG 65 In Stock
10MG 110 In Stock
25MG 222 In Stock
50MG 356 In Stock
100MG 533 In Stock
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Biological Information

  • Product Name
    ML-109
  • Note
    Research use only, not for human use.
  • Brief Description
    ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)ML-109 is a full agonist at TSHR with an EC50 of 40 nM,has no activity at FSHR or LHCGR.
  • Description
    ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)ML-109 is a full agonist at TSHR with an EC50 of 40 nM ,has no activity at FSHR or LHCGR.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    thyrotropin receptor (TSHR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1186649-91-1
  • Formula Weight
    523.58
  • Molecular Formula
    C31H29N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:83.33 mg/mL (159.15 mM; Need ultrasonic)
  • SMILES
    COc1ccc(cc1COc1ccc(NC(C)=O)cc1)C1Nc2cccc(O)c2C(=O)N1Cc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12471-6.
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