ML115

CAS No. 912798-42-6

ML115( —— )

Catalog No. M28043 CAS No. 912798-42-6

ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 252 In Stock
5MG 227 In Stock
10MG 359 In Stock
25MG 630 In Stock
50MG 863 In Stock
100MG 1163 In Stock
200MG 1562 In Stock
500MG 2306 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ML115
  • Note
    Research use only, not for human use.
  • Brief Description
    ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
  • Description
    ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    Apoptosis|Reactive Oxygen Species
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    912798-42-6
  • Formula Weight
    322.75
  • Molecular Formula
    C15H15ClN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20 mg/mL (61.97 mM)
  • SMILES
    COc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nikoloff N, et al. Flurochloridone-based herbicides induced genotoxicity effects on Rhinella arenarum tadpoles (Anura: Bufonidae). Ecotoxicol Environ Saf. 2014 Feb;100:275-81.
molnova catalog
related products
  • ALS-8112

    ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM.

  • NT219

    NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylation NT219 is useful for the study of cancer and neurodegenerative diseases.

  • N-Methylcytisine

    N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).