ML115
CAS No. 912798-42-6
ML115( —— )
Catalog No. M28043 CAS No. 912798-42-6
ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 252 | In Stock |
|
| 5MG | 227 | In Stock |
|
| 10MG | 359 | In Stock |
|
| 25MG | 630 | In Stock |
|
| 50MG | 863 | In Stock |
|
| 100MG | 1163 | In Stock |
|
| 200MG | 1562 | In Stock |
|
| 500MG | 2306 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML115
-
NoteResearch use only, not for human use.
-
Brief DescriptionML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
-
DescriptionML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayJAK/STAT Signaling
-
TargetSTAT
-
RecptorApoptosis|Reactive Oxygen Species
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number912798-42-6
-
Formula Weight322.75
-
Molecular FormulaC15H15ClN2O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20 mg/mL (61.97 mM)
-
SMILESCOc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Nikoloff N, et al. Flurochloridone-based herbicides induced genotoxicity effects on Rhinella arenarum tadpoles (Anura: Bufonidae). Ecotoxicol Environ Saf. 2014 Feb;100:275-81.
molnova catalog
related products
-
ALS-8112
ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM.
-
NT219
NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylation NT219 is useful for the study of cancer and neurodegenerative diseases.
-
N-Methylcytisine
N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).
Cart
sales@molnova.com