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ML-241
CAS No. 1346528-06-0
ML-241 ( ML 241;ML241 )
Catalog No. M11397 CAS No. 1346528-06-0
ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 70 | In Stock |
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| 10MG | 113 | In Stock |
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| 25MG | 249 | In Stock |
|
| 50MG | 421 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML-241
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NoteResearch use only, not for human use.
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Brief DescriptionML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
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DescriptionML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM; induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.
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SynonymsML 241;ML241
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PathwayProteasome/Ubiquitin
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Targetp97
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Recptorp97
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Research Area——
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Indication——
Chemical Information
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CAS Number1346528-06-0
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Formula Weight372.46
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Molecular FormulaC23H24N4O
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC1CCC2=C(C1)C(=NC(=N2)N3CCOC4=CC=CC=C43)NCC5=CC=CC=C5
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Chemical NameN-benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.
molnova catalog
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