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ML-240
CAS No. 1346527-98-7
ML-240 ( ML 240;ML-240 )
Catalog No. M11396 CAS No. 1346527-98-7
ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 41 | In Stock |
|
| 5MG | 67 | In Stock |
|
| 10MG | 106 | In Stock |
|
| 25MG | 223 | In Stock |
|
| 50MG | 388 | In Stock |
|
| 100MG | 574 | In Stock |
|
| 500MG | 1224 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML-240
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NoteResearch use only, not for human use.
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Brief DescriptionML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
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DescriptionML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks degradation of p97-dependent proteasome substrate with an IC50 of 0.9 uM; induces caspases 3 and 7 and potently blocked proliferation in HCT15 and SW403 cells.
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SynonymsML 240;ML-240
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PathwayProteasome/Ubiquitin
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Targetp97
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RecptorP97
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1346527-98-7
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Formula Weight396.44
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Molecular FormulaC23H20N6O
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Purity>98% (HPLC)
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SolubilityDMSO: 16.5 mg/mL
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SMILESCOC1=CC=CC2=C(NCC3=CC=CC=C3)N=C(N4C5=CC=CC=C5N=C4N)N=C12
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Chemical Name4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Bastola P, et al. Mol Oncol. 2016 Dec;10(10):1559-1574.
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Bastola P, et al. Mol Oncol. 2016 Dec;10(10):1559-1574.
molnova catalog
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DBEQ
DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.
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ML-241
ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
