ML-148
CAS No. 451496-96-1
ML-148 ( —— )
Catalog No. M28159 CAS No. 451496-96-1
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 170 | Get Quote |
|
10MG | 267 | Get Quote |
|
25MG | 483 | Get Quote |
|
50MG | 698 | Get Quote |
|
100MG | 972 | Get Quote |
|
500MG | 1953 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameML-148
-
NoteResearch use only, not for human use.
-
Brief DescriptionML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).
-
DescriptionML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.(In Vitro):ML148 (10 nM) reduces the apparent Km by half and decreases Vmax by 25%. ML148 shows selectivity with IC50s of 36000, >57500, >57500 nM for ALDH1A1, HADH2, HSD17β4, respectively.
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
RecptorGPR52
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number451496-96-1
-
Formula Weight319.4
-
Molecular FormulaC20H21N3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C=1C=CC2=C(N=CN2C3=CC=CC(=C3)C)C1)N4CCCCC4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Wang, C., Zhang, Y.-F., Guo, S., et al.GPR52 antagonist reduces huntingtin levels and ameliorates Huntington’s disease-related phenotypesJ. Med. Chem.64(2)941-957(2021)
molnova catalog
related products
-
Succinyl phosphonate...
Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC).
-
Tenuifoliside C
Tenuifoliside C isolated from polygala tenuifolia willd is a target lactate dehydrogenase inhibitor. It significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
-
Lithium citrate trib...
Lithium Citrate is the active component of Lithium which is a drug used in treatment of psychiatric disease.