Cart
sales@molnova.com
MKC-1
CAS No. 125313-92-0
MKC-1 ( —— )
Catalog No. M28925 CAS No. 125313-92-0
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 192 | Get Quote |
|
| 10MG | 282 | Get Quote |
|
| 25MG | 488 | Get Quote |
|
| 50MG | 704 | Get Quote |
|
| 100MG | 981 | Get Quote |
|
| 500MG | 1971 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMKC-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionMKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle.
-
DescriptionMKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle.
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number125313-92-0
-
Formula Weight400.4
-
Molecular FormulaC22H16N4O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cc(ccc23)[N+]([O-])=O)c2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hyland EE, et al. Unified Access to Pyrimidines and Quinazolines Enabled by N-N Cleaving Carbon Atom Insertion. J Am Chem Soc. 2022 Oct 26;144(42):19258-19264.
molnova catalog
related products
-
PDK4-IN-1 hydrochlor...
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).
-
CNX-774
CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).
-
Methylisoindigotin
Meisoindigo(Natura-α; N-Methylisoindigotin; Dian III), a derivative of Indigo naturalis, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
