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SPOP-IN-6lc
CAS No. 2136270-56-7
SPOP-IN-6lc( —— )
Catalog No. M36313 CAS No. 2136270-56-7
SPOP-IN-6lc is a potent SPOP inhibitor with multiple roles in cancer, oncostatic in a variety of tumors, but functions as an oncogene in renal cancer.SPOP-IN-6lc can be used to study cell signaling and apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 275 | In Stock |
|
| 10MG | 411 | In Stock |
|
| 25MG | 825 | In Stock |
|
| 50MG | 1190 | In Stock |
|
| 100MG | 1637 | In Stock |
|
| 200MG | 2204 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSPOP-IN-6lc
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NoteResearch use only, not for human use.
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Brief DescriptionSPOP-IN-6lc is a potent SPOP inhibitor with multiple roles in cancer, oncostatic in a variety of tumors, but functions as an oncogene in renal cancer.SPOP-IN-6lc can be used to study cell signaling and apoptosis.
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DescriptionSPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number2136270-56-7
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Formula Weight505.64
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Molecular FormulaC26H31N7O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(CC1=CC=CS1)N2C3=C(C(=O)N4C(=N3)C(C)=CC=C4)C=C(C(NCCN5CCN(C)CC5)=O)C2=N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dong Z, et al. Structure-Activity Relationship of SPOP Inhibitors against Kidney Cancer. J Med Chem. 2020 May 14;63(9):4849-4866. ?
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