MK-8719

CAS No. 1382799-40-7

MK-8719( —— )

Catalog No. M23538 CAS No. 1382799-40-7

MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 In Stock
10MG 295 In Stock
25MG 502 In Stock
50MG 709 In Stock
100MG 1008 In Stock
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Biological Information

  • Product Name
    MK-8719
  • Note
    Research use only, not for human use.
  • Brief Description
    MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
  • Description
    MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    O-GlcNAcase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1382799-40-7
  • Formula Weight
    268.28
  • Molecular Formula
    C9H14F2N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O[C@H]1[C@H](O)[C@@]2([H])N=C(NCC)S[C@@]2([H])O[C@@H]1C(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Selnick HG, et al. Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J Med Chem. 2019 Sep 29.
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