MK-8719

CAS No. 1382799-40-7

MK-8719( —— )

Catalog No. M23538 CAS No. 1382799-40-7

MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 In Stock
10MG 295 In Stock
25MG 502 In Stock
50MG 709 In Stock
100MG 1008 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    MK-8719
  • Note
    Research use only, not for human use.
  • Brief Description
    MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
  • Description
    MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    O-GlcNAcase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1382799-40-7
  • Formula Weight
    268.28
  • Molecular Formula
    C9H14F2N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O[C@H]1[C@H](O)[C@@]2([H])N=C(NCC)S[C@@]2([H])O[C@@H]1C(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Selnick HG, et al. Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J Med Chem. 2019 Sep 29.
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