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MK-212
CAS No. 61655-58-1
MK-212( MK 212 | MK212 )
Catalog No. M15329 CAS No. 61655-58-1
A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 58 | Get Quote |
|
| 10MG | 80 | Get Quote |
|
| 25MG | 192 | Get Quote |
|
| 50MG | 356 | Get Quote |
|
| 100MG | 530 | Get Quote |
|
| 500MG | 1152 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMK-212
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A.
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DescriptionA potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A; stimulates phosphoinositide hydrolysis in cerebral cortex, antagonizes the analgesia induced by either morphine or THIP in vivo.
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In Vitro——
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In Vivo——
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SynonymsMK 212 | MK212
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number61655-58-1
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Formula Weight235.12
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Molecular FormulaC8H11ClN4.HCl
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 10 mg/mL (42.53 mM)
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SMILESClC1=CN=CC(N2CCNCC2)=N1.[H]Cl
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Chemical Name6-Chloro-2-(1-piperazinyl)pyrazine hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Conn PJ, et al. J Pharmacol Exp Ther. 1987 Aug;242(2):552-7.
2. Hemrick-Luecke SK, et al. Eur J Pharmacol. 1996 Sep 12;311(2-3):207-11.
3. Jensen AA, et al. J Med Chem. 2013 Feb 14;56(3):1211-27.
4. Murray TF, et al. Eur J Pharmacol. 1983 Jun 3;90(2-3):179-84.
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