MK-212

CAS No. 61655-58-1

MK-212( MK 212 | MK212 )

Catalog No. M15329 CAS No. 61655-58-1

A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 58 Get Quote
10MG 80 Get Quote
25MG 192 Get Quote
50MG 356 Get Quote
100MG 530 Get Quote
500MG 1152 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    MK-212
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A.
  • Description
    A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A; stimulates phosphoinositide hydrolysis in cerebral cortex, antagonizes the analgesia induced by either morphine or THIP in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MK 212 | MK212
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    61655-58-1
  • Formula Weight
    235.12
  • Molecular Formula
    C8H11ClN4.HCl
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 10 mg/mL (42.53 mM)
  • SMILES
    ClC1=CN=CC(N2CCNCC2)=N1.[H]Cl
  • Chemical Name
    6-Chloro-2-(1-piperazinyl)pyrazine hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Conn PJ, et al. J Pharmacol Exp Ther. 1987 Aug;242(2):552-7. 2. Hemrick-Luecke SK, et al. Eur J Pharmacol. 1996 Sep 12;311(2-3):207-11. 3. Jensen AA, et al. J Med Chem. 2013 Feb 14;56(3):1211-27. 4. Murray TF, et al. Eur J Pharmacol. 1983 Jun 3;90(2-3):179-84.
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