MK-212 ( MK 212;MK212 )

Catalog No. M15329 CAS No. 61655-58-1

A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	58	Get Quote
10MG	80	Get Quote
25MG	192	Get Quote
50MG	356	Get Quote
100MG	530	Get Quote
500MG	1152	Get Quote
1G	Get Quote	Get Quote

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

MK-212
Note

Research use only, not for human use.
Brief Description

A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A.
Description

A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A; stimulates phosphoinositide hydrolysis in cerebral cortex, antagonizes the analgesia induced by either morphine or THIP in vivo.
Synonyms

MK 212;MK212
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

61655-58-1
Formula Weight

235.12
Molecular Formula

C8H11ClN4.HCl
Purity

>98% (HPLC)
Solubility

——
SMILES

ClC1=CN=CC(N2CCNCC2)=N1.[H]Cl
Chemical Name

6-Chloro-2-(1-piperazinyl)pyrazine hydrochloride

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Conn PJ, et al. J Pharmacol Exp Ther. 1987 Aug;242(2):552-7.
2. Hemrick-Luecke SK, et al. Eur J Pharmacol. 1996 Sep 12;311(2-3):207-11.
3. Jensen AA, et al. J Med Chem. 2013 Feb 14;56(3):1211-27.
4. Murray TF, et al. Eur J Pharmacol. 1983 Jun 3;90(2-3):179-84.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks