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MCI-225

CAS No. 135991-48-9

MCI-225 ( —— )

Catalog No. M21940 CAS No. 135991-48-9

MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.MCI-225 (10 mg/kg, po) showed comparable anxiolytic-like effect between single and 5-day repeated administration.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 267 In Stock
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25MG 672 In Stock
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Biological Information

  • Product Name
    MCI-225
  • Note
    Research use only, not for human use.
  • Brief Description
    MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.MCI-225 (10 mg/kg, po) showed comparable anxiolytic-like effect between single and 5-day repeated administration.?
  • Description
    MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.MCI-225 (10 mg/kg, po) showed comparable anxiolytic-like effect between single and 5-day repeated administration.?
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NA reuptake
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    135991-48-9
  • Formula Weight
    328.4
  • Molecular Formula
    C17H17FN4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1cc2c(nc(nc2s1)N1CCNCC1)-c1ccccc1F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Eguchi J , Inomata Y , Saito K I . The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism[J]. Pharmacology Biochemistry & Behavior, 2001, 68(4):677-683. 2. Junichi Eguchi, Kunihisa Iwai, Takayuki Yuasa,et al. Effects of MCI-225 on memory and glucose utilization in basal forebrain-lesioned rats[J]. Pharmacology Biochemistry and Behavior, 1995, 51(4):935-939.
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