Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - HDAC - MC-1568

MC-1568

CAS No. 852475-26-4

MC-1568 ( MC1568 )

Catalog No. M16194 CAS No. 852475-26-4

A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 47 In Stock
25MG 85 In Stock
50MG 131 In Stock
100MG 236 In Stock
200MG 410 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MC-1568
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
  • Description
    A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.
  • Synonyms
    MC1568
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HD1-A(Maize);HD1-B(Maize)
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    852475-26-4
  • Formula Weight
    314.31
  • Molecular Formula
    C17H15FN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 18.5 mg/mL
  • SMILES
    O=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
  • Chemical Name
    2-Propenamide, 3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mai A, et al. J Med Chem. 2005 May 5;48(9):3344-53.
2. Duong V, et al. Mol Cancer Res. 2008 Dec;6(12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015;51(3):1432-42.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Apicidin

    Apicidin (OSI 2040) is a fungal metabolite that exhibits potent, broad spectrum antiprotozoal activity in vitro.

  • BRD4354

    BRD4354 is a moderately potent, selective, reversible inhibitor of HDAC5 and HDAC9 with IC50 of 0.85 uM and 1.88 uM.

  • Panobinostat

    A potent, broad-spectrum HDAC inhibitor with IC50 of 5-20 nM in cell-free assyas.

Sign In Join Free