Cart
sales@molnova.com
Home - Products - Others - Other Targets - MAO-B-IN-5

MAO-B-IN-5

CAS No. 849909-77-9

MAO-B-IN-5( —— )

Catalog No. M37657 CAS No. 849909-77-9

MAO-B-IN-5 is a potent, selective, and orally active MAO-B inhibitor with an IC50 of 0.204 μM, showing potential for research in Parkinson's disease (PD) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 236 Get Quote
5MG 366 Get Quote
10MG 521 Get Quote
25MG 756 Get Quote
50MG 1021 Get Quote
100MG 1350 Get Quote
200MG 1764 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MAO-B-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    MAO-B-IN-5 is a potent, selective, and orally active MAO-B inhibitor with an IC50 of 0.204 μM, showing potential for research in Parkinson's disease (PD) .
  • Description
    MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC50 of 0.204 μM. MAO-B-IN-5 has the potential for the research of Parkinson's disease (PD).
  • In Vitro
    MAO-B-IN-5 (compound D0) (Sf9 cells) shows inhibitory activities towards MAO with the IC50s of 34.190 μM and 0.204 μM for MAO-A and MAO-B, respectively.
  • In Vivo
    MAO-B-IN-5 (1 mg/kg, i.v.; 5 mg/kg, p.o.) shows oral bioavailability in rats (F=13.6%).Pharmacokinetic Parameters of MAO-B-IN-5 in SD rats.SD rats; 1 mg/kg, i.v.; 5 mg/kg, p.o..Animal Model:SD rats Dosage:1, 5 mg/kg Administration:1 mg/kg, i.v.; 5 mg/kg, p.o.Result:Showed oral bioavailability in rats (F=16.3%).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    849909-77-9
  • Formula Weight
    328.38
  • Molecular Formula
    C19H21FN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N1[C@H](C(N)=O)CCC1)C2=CC=C(OCC3=CC(F)=CC=C3)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang Z,et al. Enhancing monoamine oxidase B inhibitory activity via chiral fluorination: Structure-activity relationship, biological evaluation, and molecular docking study. Eur J Med Chem. 2022; 228:114025.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 24-Dichlorophenol

    24-Dichlorophenol is the precursor to the herbicide 24-dichlorophenoxyacetic acid (24-D).

  • 3-Chloro-L-Tyrosine

    3-Chlorotyrosine a specific marker of myeloperoxidase-catalyzed oxidation is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY).

  • 3-O-[5-O-feruloyl-be...

    3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin is a natural product for research related to life sciences.

Sign In Join Free