Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research.

Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.

Bidenoside C is a flavonoid found in brazilian propolis, the first of its kind to be isolated from a herb of the genus Leech, and has anti-proliferative activity against cancer cells.