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GSK-J2

CAS No. 1394854-52-4

GSK-J2( —— )

Catalog No. M32949 CAS No. 1394854-52-4

GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 103 In Stock
5MG 65 In Stock
10MG 93 In Stock
25MG 160 In Stock
50MG 230 In Stock
100MG 339 In Stock
200MG 504 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    GSK-J2
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.
  • Description
    GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
  • In Vitro
    GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC50 of > 100 μM and 49 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1394854-52-4
  • Formula Weight
    389.45
  • Molecular Formula
    C22H23N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 42 mg/mL (107.84 mM )
  • SMILES
    O=C(O)CCNC=1N=C(N=C(C1)N2CCC=3C=CC=CC3CC2)C4=CN=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2?
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