Cart
sales@molnova.com
Antagonist G
CAS No. 115150-59-9
Antagonist G( ——— )
Catalog No. M41872 CAS No. 115150-59-9
Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 229 | In Stock |
|
| 10MG | 371 | In Stock |
|
| 25MG | Get Quote | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAntagonist G
-
NoteResearch use only, not for human use.
-
Brief DescriptionAntagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy.
-
DescriptionAntagonist G is an anticancer peptide and is also a broad spectrum neuropeptide growth factor antagonist.
-
In VitroAntagonist G (0-100 μM) induces apoptosis is redox-sensitive and caspase-dependently in SCLC cells.Antagonist G activates JNK1 in SCLC cells.Antagonist G is not intrinsically a free radical oxygen donor but stimulates free radical generation specifically within SCLC cells (6.2-fold) and increases the activity of the redox-sensitive transcription factor AP-1 by 61%.Cell Viability Assay Cell Line:SCLC cell lines NCI-H69, NCI-H510 and CHO-K1 cells.Concentration:0-100 μM.Incubation Time:24 h.
-
In Vivo———
-
Synonyms———
-
PathwayOthers
-
TargetOther Targets
-
Recptor———
-
Research Area———
-
Indication———
Chemical Information
-
CAS Number115150-59-9
-
Formula Weight951.2
-
Molecular FormulaC49H62O6N12S
-
Purity>98% (HPLC)
-
SolubilityH2O : 50 mg/mL (52.57 mM; ultraphonic)
-
SMILES———
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. P J Woll, et al. A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro. Cancer Res. 1990 Jul 1;50(13):3968-73.?
molnova catalog
related products
-
Xinidamine
Xinidamine (BRN 0891979) has antitumor activity and can be used to study benign prostatic hyperplasia, macular degeneration and prostatic intraepithelial neoplasia .
-
ND-646
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)ND-646-an allosteric inhibitor of the ACC enzymes. ACC1 and ACC2 that prevents ACC subunit dimerization-to suppress fatty acid synthesis in vitro and in vivo.?
-
OSMI-4
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor (EC50 of 3 μM in cells) that can be used to study OGT inhibition in different human cell lines.
