Humanin (human)( ——— )

Catalog No. M41825 CAS No. 330936-69-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Humanin (human)
Note

Research use only, not for human use.
Brief Description

Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging. Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG.
Description

Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity.
In Vitro

———
In Vivo

———
Synonyms

———
Pathway

Others
Target

Other Targets
Recptor

Bax
Research Area

———
Indication

———

CAS Number

330936-69-1
Formula Weight

2687.28
Molecular Formula

C119H204N34O32S2
Purity

>98% (HPLC)
Solubility

DMSO : 100 mg/mL (37.21 mM; ultraphonic; ) H2O : 50 mg/mL (18.61 mM; ultraphonic)
SMILES

———
Chemical Name

——