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Artemisitene

CAS No. 101020-89-7

Artemisitene( —— )

Catalog No. M23216 CAS No. 101020-89-7

Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 312 In Stock
25MG 530 In Stock
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Biological Information

  • Product Name
    Artemisitene
  • Note
    Research use only, not for human use.
  • Brief Description
    Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent.
  • Description
    Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisinic acid, etc.
  • In Vitro
    Artemisitene selectively induces DNA double-stranded breaks (DSBs) and apoptosis in various human cancer cells by suppressing the expression of topoisomerases in human cancer cells. Artemisitene selectively destabilizes c-Myc in human cancer cells by promoting the ubiquitination of c-Myc through the specific induction of the c-Myc E3 ligase NEDD4.
  • In Vivo
    In Nrf2 wild-type mice, systemic administration of Artemisitene (5-10 mg/kg; i.p.) strongly inhibits bleomycin-induced lung damage.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    101020-89-7
  • Formula Weight
    280.32
  • Molecular Formula
    C15H20O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    C[C@H](CCC1C2=C)[C@H](CC3)[C@]11OO[C@@]3(C)O[C@H]1OC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li Y, Wu YL. An over four millennium story behind qinghaosu (artemisinin)--a fantastic antimalarial drug from a traditional chinese herb. Curr Med Chem. 2003 Nov;10(21):2197-230.
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