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Hepcidin-1 (mouse) trifluoroacetate salt

CAS No. 1676104-75-8

Hepcidin-1 (mouse) trifluoroacetate salt( ——— )

Catalog No. M41734 CAS No. 1676104-75-8

Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Hepcidin-1 (mouse) trifluoroacetate salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation.
  • Description
    Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion.
  • In Vitro
    Western Blot Analysis Cell Line:RAW264.7 cells Concentration:0, 200, 400, or 800 nM Incubation Time:20 h Result:Decreased Ferroportin 1 (FPN1) protein.Real Time qPCR Cell Line:RAW264.7 cells Concentration:0, 200, 400, or 800 nM Incubation Time:4 days Result:Increased the gene expression of TRAP, CTK, and MMP-9 in a dose-dependent manner.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MMP-9, cathepsin K
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    1676104-75-8
  • Formula Weight
    2754.28
  • Molecular Formula
    C111H169N31O35S8
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhao GY, et al. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration. Inflammation. 2015 Apr;38(2):718-27.?
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