6-Hydroxyluteolin (Compound 17) is a flavonoid compound. 6-Hydroxyluteolin has an inhibitory effect on aldose reductase (AR) .

KL-50 is a selective toxin toward tumors that lack the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O6-alkylguanine lesions. KL-50 activates DNA damage response pathways and cycle arrest in MGMT-cells, independent of mismatch repair (MMR). KL-50 is promising for research of brain tumors that lack the DNA repair protein MGMT.

1-beta-D-Arabinofuranosyluracil isolated from the Caribbean sponge Tectitethya crypta is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has anti-inflammatory activity analgesic and vasodilation properties.