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Thalidomide 4'-ether-alkylC2-amine hydrochloride

CAS No. 2341840-99-9

Thalidomide 4'-ether-alkylC2-amine hydrochloride( halidomide-linker 6 )

Catalog No. M28270 CAS No. 2341840-99-9

Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 72 Get Quote
25MG 147 Get Quote
50MG 237 Get Quote
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Biological Information

  • Product Name
    Thalidomide 4'-ether-alkylC2-amine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate.
  • Description
    Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    halidomide-linker 6
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MMP-12
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2341840-99-9
  • Formula Weight
    353.76
  • Molecular Formula
    C15H16ClN3O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (353.35 mM)
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCN)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wei Li, et al. A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408). Journal of Medicinal Chemistry 2009 52 (7), 1799-1802
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