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AKT/PKB/Rac - Protein Kinase Substrate

CAS No. 324029-01-8

AKT/PKB/Rac - Protein Kinase Substrate( ——— )

Catalog No. M41669 CAS No. 324029-01-8

AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AKT/PKB/Rac - Protein Kinase Substrate
  • Note
    Research use only, not for human use.
  • Brief Description
    AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position.
  • Description
    Peptide substrate for Akt/PKB
  • In Vitro
    AKTide-2T mimics the optimal phosphorylation sequence of Akt, and inhibits Akt phosphorylated Hsp27 by addition of 20 μM Akt inhibitory peptide.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    324029-01-8
  • Formula Weight
    1715.87
  • Molecular Formula
    C74H114N28O20
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. T Obata,et al. Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J Biol Chem. 2000 Nov 17;275(46):36108-15.?
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