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[D-Pro2,D-Phe7,D-Trp9]-Substance P

CAS No. 77275-70-8

[D-Pro2,D-Phe7,D-Trp9]-Substance P( ——— )

Catalog No. M41635 CAS No. 77275-70-8

[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    [D-Pro2,D-Phe7,D-Trp9]-Substance P
  • Note
    Research use only, not for human use.
  • Brief Description
    [D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.
  • Description
    [D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.
  • In Vitro
    [D-Pro2,D-Phe7,D-Trp9] Substance P (10-100 μM; 2 min or 10 min) produces dose-related contractions of the guinea-pig ileum and in the rabbit external jugular vein.
  • In Vivo
    [D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Substance P
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    77275-70-8
  • Formula Weight
    1476.82
  • Molecular Formula
    C72H105N19O13S
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hawcock AB, et al. Agonist effects of D-Pro2,D-Phe7,D-Trp9substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80(1):135-8.?
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