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[D-Pro2,D-Trp6,8,Nle10]-Neurokinin B
CAS No. 109212-72-8
[D-Pro2,D-Trp6,8,Nle10]-Neurokinin B( ——— )
Catalog No. M41434 CAS No. 109212-72-8
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name[D-Pro2,D-Trp6,8,Nle10]-Neurokinin B
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NoteResearch use only, not for human use.
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Brief Description(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A.
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Description(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A.
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In Vitro———
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In Vivo(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) significantly reduces Substance P- and Neurokinin B- but not acetylcholine- or Neurokinin A-induced salivation. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B lowers blood pressure in anesthetized rats by 35 to 40%.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number109212-72-8
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Formula Weight1326.53
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Molecular FormulaC67H87N15O14
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. H I Jacoby, et al. Differentiation of multiple neurokinin receptors in the guinea pig ileum. Life Sci. 1986 Nov 24;39(21):1995-2003. ?
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