Prim-O-glucosylcimifugin can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.

3'-Hydroxy-4'-methoxyacetophenone is an active P. spinosa extract. It possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.

4-Methoxycinnamaldehyde is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cell lines, and helps to control disease induced by RSV infection, with an IC50 of approximately 0.055 μg/mL. The IC50 was about 0.055 μg/mL.