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[Tyr22] - a - CGRP (22 - 37), rat
CAS No. 198277-54-2
[Tyr22] - a - CGRP (22 - 37), rat( ——— )
Catalog No. M41005 CAS No. 198277-54-2
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name[Tyr22] - a - CGRP (22 - 37), rat
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NoteResearch use only, not for human use.
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Brief Description[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system.
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Description[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system.
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In VitroCalcitonin Gene Related Peptide (CGRP) in humans, exists in two forms: CGRP alpha (α-CGRP or CGRP I), and CGRP beta (β-CGRP or CGRP II).[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat shows the receptor binding affinity mainly depending on the carboxyterminal end while the ability to stimulate adenylate cyclase (AC) enzyme mainly depending on the aminoterminal end.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number198277-54-2
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Formula Weight1785.99
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Molecular FormulaC82H120N20O25
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL (55.99 mM; ultraphonic; )
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jia S, et al. Calcitonin gene-related peptide enhances osteogenic differentiation and recruitment of bone marrow mesenchymal stem cells in rats. Exp Ther Med. 2019 Aug;18(2):1039-1046. ?
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