[Sar1,Ile4,8]-Angiotensin II
CAS No. 185461-45-4
[Sar1,Ile4,8]-Angiotensin II( ——— )
Catalog No. M40844 CAS No. 185461-45-4
(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 79 | In Stock |
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| 10MG | 126 | In Stock |
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| 25MG | Get Quote | In Stock |
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| 50MG | Get Quote | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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Biological Information
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Product Name[Sar1,Ile4,8]-Angiotensin II
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NoteResearch use only, not for human use.
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Brief Description(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β.
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Description(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β.
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In Vitro———
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorAngiotensin II Type 1
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Research Area———
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Indication———
Chemical Information
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CAS Number185461-45-4
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Formula Weight918.15
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Molecular FormulaC43H75N13O9
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Purity>98% (HPLC)
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SolubilityH2O : 100 mg/mL (108.92 mM; ultraphonic)
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sanni SJ, et al. Sar1, Ile4, Ile8-angiotensin II Potentiates Insulin Receptor Signalling and Glycogen Synthesis in Hepatocytes. Basic Clin Pharmacol Toxicol. 2018 May;122(5):460-469.?
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