RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.

5-Methoxyresorcinol is a chemical intermediate.

This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area. The primary structures of human, rat, and frog 26RFa exhibit ≈80% identity. Other data suggest also the potential role of the 26RFa peptide in the control of the gonadotropic axis.