(Met(O)27)-Glucagon (1-29) (human, rat, porcine)( ——— )

Catalog No. M40228 CAS No. 75217-63-9

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Product Name

(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
Note

Research use only, not for human use.
Brief Description

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor.
Description

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor.
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In Vivo

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Indication

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1. Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63.?

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