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Stichodactyla helianthus Neurotoxin (ShK)
CAS No. 172450-46-3
Stichodactyla helianthus Neurotoxin (ShK)( ——— )
Catalog No. M40092 CAS No. 172450-46-3
ShK toxin blocks voltage-dependent potassium channel (Kv1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameStichodactyla helianthus Neurotoxin (ShK)
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NoteResearch use only, not for human use.
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Brief DescriptionShK toxin blocks voltage-dependent potassium channel (Kv1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation.
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DescriptionShK toxin blocks voltage-dependent potassium channel (Kv1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus).
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In Vitro———
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorKv1.3 Channel
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Research Area———
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Indication———
Chemical Information
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CAS Number172450-46-3
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Formula Weight4054.8
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Molecular FormulaC169H274N54O48S7
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Casta?eda O, et al. Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus. Toxicon. 1995 May;33(5):603-13.?
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