Senkyunolide N exhibits prostaglandin H endoperoxide synthase-I (COX-I) and endoperoxide synthase-II (COX-II)) Inhibitory activity at pH 7 and at a concentration of 250 pg ml(-1) .

HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).HLM006474 causes the viability of both SCLC and NSCLC lines (IC50 ranging from 15 to 75 μM). HLM006474 displays little activities against E2F4 DNA-binding in A375 cells at 10 and 20 μM, apparently inhibits E2F4 DNA-binding at 40 μM, and increasingly suppresses the effect at 60 and 80 μM concentrations.

Safflospermidine B is a natural product.