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(S,R,S)-AHPC-C10-NH2 dihydrochloride
CAS No. 2341796-75-4
(S,R,S)-AHPC-C10-NH2 dihydrochloride( VH032-C10-NH2 dihydrochloride | VH032-linker 10 | VH032 amide-alkylC10-amine )
Catalog No. M27012 CAS No. 2341796-75-4
(S,R,S)-AHPC-C10-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 302 | Get Quote |
|
| 10MG | 447 | Get Quote |
|
| 25MG | 808 | Get Quote |
|
| 50MG | 1226 | Get Quote |
|
| 100MG | 1797 | Get Quote |
|
| 200MG | 2695 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product Name(S,R,S)-AHPC-C10-NH2 dihydrochloride
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NoteResearch use only, not for human use.
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Brief Description(S,R,S)-AHPC-C10-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
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Description(S,R,S)-AHPC-C10-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsVH032-C10-NH2 dihydrochloride | VH032-linker 10 | VH032 amide-alkylC10-amine
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2341796-75-4
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Formula Weight686.78
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Molecular FormulaC33H53Cl2N5O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (364.02 mM)
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SMILESCl.Cl.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Morrone CD, et al. Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease. PLoS One. 2016 Oct 21;11(10):e0165393.
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