Kyotorphin

CAS No. 70904-56-2

Kyotorphin( ——— )

Catalog No. M39988 CAS No. 70904-56-2

Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 123 In Stock
10MG 211 In Stock
25MG Get Quote In Stock
50MG Get Quote In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Kyotorphin
  • Note
    Research use only, not for human use.
  • Brief Description
    Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients.
  • Description
    Kyotorphin is a Morphine-like dipeptide.
  • In Vitro
    The analgesic effect of kyotorphin is determined by means of the hot-plate test, with an ED50 value of 5.3 μg/animal (15.7 nmole/animal).
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    70904-56-2
  • Formula Weight
    337.4
  • Molecular Formula
    C15H23N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 125 mg/mL (370.51 mM; ultraphonic; ) H2O : 100 mg/mL (296.41 mM; ultraphonic)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Takagi H, et al. Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. Eur J Pharmacol. 1979;55(1):109-111.?
molnova catalog
related products
  • Dynorphin B (1-9)

    Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. The formation of dynorphin B (1-9) is blocked by N-ethylmaleimide (NEM), a non-selective inhibitor of cysteine peptidases.

  • Cltrinin

    Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity.

  • m-PEG2-Br

    m-PEG2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.