Cecropin P1 (porcine)

CAS No. 125667-96-1

Cecropin P1 (porcine)( ——— )

Catalog No. M39884 CAS No. 125667-96-1

Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cecropin P1 (porcine)
  • Note
    Research use only, not for human use.
  • Brief Description
    Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection.
  • Description
    Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection.
  • In Vitro
    Cell Viability Assay Cell Line:Marc-145 cells Concentration:160, 320, and 480 μg/mL Incubation Time:36, 48, 72, 96 h Result:Significantly inhibited viral infection in a dose-dependent manner at 36 h postinfection. Inhibited CH-1a infection in Marc-145 cells with a 50% effective concentration (EC50) of 112 μg/mL. The 50% cytotoxic concentration (CC50) of Cecropin P1 for Marc-145 cells was estimated to be 719 μg/mL.Western Blot Analysis Cell Line:Marc-145 cells Concentration:160, 320, and 480 μg/mL Incubation Time:36 h Result:Significantly inhibited viral infection in a dose-dependent manner at 36 h postinfection. Significantly reduced the expression of the viral N protein when administered with either the pre-, co-, or posttreatment method.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    125667-96-1
  • Formula Weight
    3338.93
  • Molecular Formula
    C147H253N46O43
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 50 mg/mL (14.98 mM; ultraphonic)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Andersson M, et al. Ascaris nematodes from pig and human make three antibacterial peptides: isolation of cecropin P1 and two ASABF peptides. Cell Mol Life Sci. 2003 Mar;60(3):599-606. ?
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