Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death.

Bullatine B shows analgesic/anti-inflammatory properties.

Cassiaside C is a naphthopyrone isolated from the seed of Cassia tora. It has inhibitory activity on advanced glycation end products (AGE)?formation in vitro.