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16-dimethyl PGE2
CAS No. 39746-25-3
16-dimethyl PGE2( ——— )
Catalog No. M39447 CAS No. 39746-25-3
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name16-dimethyl PGE2
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NoteResearch use only, not for human use.
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Brief Description16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
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Description16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
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In Vitro———
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In VivoAnimal Model:Tpl2IMF-KO mice Dosage:10 μg/kg Administration:IP; every 12 hours; for 8 days Result:Rescued the exacerbated DSS colitis phenotype and restores epithelial proliferation and structure.
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Synonyms———
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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RecptorEP2
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Research Area———
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Indication———
Chemical Information
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CAS Number39746-25-3
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Formula Weight380.52
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Molecular FormulaC22H36O5
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL (262.80 mM; ultraphonic; )
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.?
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