16-dimethyl PGE2

CAS No. 39746-25-3

16-dimethyl PGE2( ——— )

Catalog No. M39447 CAS No. 39746-25-3

16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    16-dimethyl PGE2
  • Note
    Research use only, not for human use.
  • Brief Description
    16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
  • Description
    16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
  • In Vitro
    ———
  • In Vivo
    Animal Model:Tpl2IMF-KO mice Dosage:10 μg/kg Administration:IP; every 12 hours; for 8 days Result:Rescued the exacerbated DSS colitis phenotype and restores epithelial proliferation and structure.
  • Synonyms
    ———
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    EP2
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    39746-25-3
  • Formula Weight
    380.52
  • Molecular Formula
    C22H36O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (262.80 mM; ultraphonic; )
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.?
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