NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.NDMC101 markedly inhibited RANKL-induced formation of TRAP+ multinucleated cells in RAW264.7 and bone marrow macrophage cells (BMMs).?

Protostemotinine is a natural product from Stemona japonica.

5-O-Coumaroylquinic acid has a considerable inhibitory effect on PTP1B.5-O-Coumaroylquinic acid( 3-O-Coumaroylquinic acid) shows a significant concentration-dependent inhibitory effect on α-glucosidase, so it has anti-hyperglycemic effect.5-O-Coumaroylquinic acid(3-O-Coumaroylquinine acid) enhances glucose uptake and inhibits PTP1B in vitro.