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Tanshinone IIB
CAS No. 17397-93-2
Tanshinone IIB( ——— )
Catalog No. M39087 CAS No. 17397-93-2
Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameTanshinone IIB
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NoteResearch use only, not for human use.
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Brief DescriptionTanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis.
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DescriptionCo-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner.
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In Vitro———
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorP-gp;Bcl-2;Caspase
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Research Area———
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Indication———
Chemical Information
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CAS Number17397-93-2
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Formula Weight310.349
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Molecular FormulaC19H18O4
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Purity>98% (HPLC)
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SolubilityMethanol : 0.5 mg/mL (1.61 mM; ultraphonic)
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Stachydrine Hydrochl...
Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.
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Cltrinin
Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity.
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16-Epivoacarpine
16-Epivoacarpine is a natural product from Gelsemium elegans.
