MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.MCI-225 (10 mg/kg, po) showed comparable anxiolytic-like effect between single and 5-day repeated administration.?

CTP Synthetase-IN-1 is an orally active and potent cytidine 5'-triphosphate synthetase (CTPS) inhibitor with potential antitumour activity, shows anti-inflammatory activity in animal models of inflammation, inhibits human CTPS1 and human CTPS2, and can be used in studies of arthritis and rheumatoid arthritis.

Lodoxamide is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.